作者: Brandon Ayers , Eileen Luders , Nicolas Cherbuin , Shantanu H. Joshi
DOI: 10.1109/ISBI.2015.7164166
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摘要: We present a shape-based approach for calculating the thickness of corpus callosum. The callosum is delineated from MRI midsagittal white matter boundary and represented as parameterized curve consisting top bottom boundaries by trained expert. are first in quotient space open curves, then elastically matched under geometric framework that generates an optimal correspondence between their “shapes”. This matching computed using geodesic shape representations invariant to reparameterizations curves. Callosal given distance points on boundaries. Our results within healthy population N = 96 subjects show significant differences callosal elastic compared direct Euclidean approach.