Loss of pRb Expression in Pituitary Adenomas Is Associated with Methylation of the RB1 CpG Island
作者： Anne Marie McNicol , Nigel A. Hibberts , David J. Simpson , William E. Farrell , Richard N. Clayton
DOI:
关键词:
摘要: … of methylated RB1 promoter sequence after modification, we … were unable to sequence exon 24 for inactivating mutations or … No methylation was found in any of the matched blood DNA …
aacrjournals.org
researchgate.net 参考文章(40)
A. Aoike, N. Ohtani-Fujita, T. Sakai, Paul D Robbins, T. Fujita, N. E. Osifchin, CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene Oncogene. ,vol. 8, pp. 1063- 1067 ,(1993)
Per Alm, Gunilla Sellberg, Qiu-Xia Zhang, Åke Borg, Håkan Olsson, The retinoblastoma gene in breast cancer: allele loss is not correlated with loss of gene protein expression. Cancer Research. ,vol. 52, pp. 2991- 2994 ,(1992)
Jill A. Macoska, Sofia D. Merajver, Kirk J. Wojno, Kathleen A. Cooney, Timothy P. Singleton, Jon C. Wetzel, Distinct Regions of Allelic Loss on 13q in Prostate Cancer Cancer Research. ,vol. 56, pp. 1142- 1145 ,(1996)
Stephen B. Baylln, James G. Herman, Jeremy R. Graff, Paula M. Vertino, Jean-Pierre Issa, ALTERATIONS IN DNA METHYLATION : A FUNDAMENTAL ASPECT OF NEOPLASIA Advances in Cancer Research. ,vol. 72, pp. 141- 196 ,(1998) , 10.1016/S0065-230X(08)60702-2
Sadao Kamidono, Jiro Ishikawa, Sakan Maeda, Hong-Ji Xu, David W. Yandell, William F. Benedict, Rei Takahashi, Shi-Xue Hu, Inactivation of the Retinoblastoma Gene in Human Bladder and Renal Cell Carcinomas Cancer Research. ,vol. 51, pp. 5736- 5743 ,(1991)
Peter A. Jones, DNA Methylation Errors and Cancer Cancer Research. ,vol. 56, pp. 2463- 2467 ,(1996)
A. M. McNicol, D. J. Simpson, W. E. Farrell, W. E. Farrell, W. E. Farrell, A. L. Barkan, J. Magnay, R. N. Clayton, J. E. Bicknell, Chromosome 13q deletion mapping in pituitary tumors: infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas. Cancer Research. ,vol. 59, pp. 1562- 1566 ,(1999)
Peter M. Warnecke, Paul C. Vincent, Marianne Frommer, Susan J. Clark, Clare Stirzaker, Douglas S. Millar, Cheryl L. Paul, Janet Harrison, Extensive DNA Methylation Spanning the Rb Promoter in Retinoblastoma Tumors Cancer Research. ,vol. 57, pp. 2229- 2237 ,(1997)
J Toguchida, T Sakai, N Ohtani, D W Yandell, T P Dryja, J M Rapaport, Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. American Journal of Human Genetics. ,vol. 48, pp. 880- 888 ,(1991)
R Bookstein, E Y Lee, A Peccei, W H Lee, Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line Molecular and Cellular Biology. ,vol. 9, pp. 1628- 1634 ,(1989) , 10.1128/MCB.9.4.1628