Three-dimensional ultrasonography measurement of fetal nasal bone length during the midtrimester in Taiwanese women

作者: Pei-Yin Yang , Joung-Liang Wu , Guang-Perng Yeh , Charles Tsung-Che Hsieh

DOI: 10.1016/J.TJOG.2012.07.006

关键词:

摘要: Abstract Objective To evaluate the normal range of fetal nasal bone length (NBL) in Taiwanese women using three-dimensional (3D) ultrasound, and compare NBL fetuses with Down syndrome to determine its significance screening for trisomy 21. Materials Methods A total 102 consecutive another 7 21, determined by karyotyping at 15–22 weeks' gestation, were evaluated 3D ultrasound before amniocentesis Changhua Christian Hospital between November 2003 April 2004. Results The second trimester population was investigated, a linear relationship gestational age noted. increased advancing (NBL cm=0.0264×gestational weeks –0.042 ( R 2 =0.2416). median biparietal diameter/nasal ratio had stable value which tended change minimally 15 22 gestation. Chromosomally statistically longer bones than p =0.014). Conclusion We present reference measurement NBL. short is associated high risk

参考文章(22)
Luís F. Gonçalves, Jimmy Espinoza, Wesley Lee, Mary Lou Schoen, Patricia Devers, Moshe Mazor, Tinnakorn Chaiworapongsa, Greggory R. DeVore, Roberto Romero, Phenotypic Characteristics of Absent and Hypoplastic Nasal Bones in Fetuses With Down Syndrome Journal of Ultrasound in Medicine. ,vol. 23, pp. 1619- 1627 ,(2004) , 10.7863/JUM.2004.23.12.1619
Min Chen, Chin Peng Lee, Kwok Yin Leung, Pui Wah Hui, Mary Hoi Yin Tang, Pilot study on the midsecond trimester examination of fetal nasal bone in the Chinese population Prenatal Diagnosis. ,vol. 24, pp. 87- 91 ,(2004) , 10.1002/PD.793
Anthony Vintzileos, Christine Walters, Lami Yeo, Absent nasal bone in the prenatal detection of fetuses with trisomy 21 in a high-risk population. Obstetrics & Gynecology. ,vol. 101, pp. 905- 908 ,(2003) , 10.1016/S0029-7844(03)00170-4
S. Cicero, J. D. Sonek, D. S. Mckenna, C. S. Croom, L. Johnson, K. H. Nicolaides, Nasal bone hypoplasia in trisomy 21 at 15-22 weeks' gestation Ultrasound in Obstetrics & Gynecology. ,vol. 21, pp. 15- 18 ,(2003) , 10.1002/UOG.19
Elisa A. Gianferrari, Peter A. Benn, Lisa Dries, Kim Brault, James F. X. Egan, Carolyn M. Zelop, Absent or shortened nasal bone length and the detection of Down Syndrome in second-trimester fetuses. Obstetrics & Gynecology. ,vol. 109, pp. 371- 375 ,(2007) , 10.1097/01.AOG.0000250903.17964.87
S. Cicero, G. Rembouskos, H. Vandecruys, M. Hogg, K. H. Nicolaides, Likelihood ratio for trisomy 21 in fetuses with absent nasal bone at the 11-14-week scan Ultrasound in Obstetrics and Gynecology. ,vol. 23, pp. 218- 223 ,(2004) , 10.1002/UOG.992
Ron Maymon, Orna Levinsohn-Tavor, Howard Cuckle, Yosef Tovbin, Eli Dreazen, Yifat Wiener, Arie Herman, Second trimester ultrasound prenasal thickness combined with nasal bone length: a new method of Down syndrome screening Prenatal Diagnosis. ,vol. 25, pp. 906- 911 ,(2005) , 10.1002/PD.1207
Anthony O. Odibo, Harish M. Sehdev, David M. Stamilio, Alison Cahill, Linda Dunn, George A. Macones, Defining nasal bone hypoplasia in second-trimester Down syndrome screening: does the use of multiples of the median improve screening efficacy? American Journal of Obstetrics and Gynecology. ,vol. 197, pp. 361- 362 ,(2006) , 10.1016/J.AJOG.2007.08.031
E. Viora, G. Errante, A. Sciarrone, S. Bastonero, B. Masturzo, G. Martiny, M. Campogrande, Fetal nasal bone and trisomy 21 in the second trimester Prenatal Diagnosis. ,vol. 25, pp. 511- 515 ,(2005) , 10.1002/PD.848