A Family Study of Panic Disorder

摘要: • In a family study of panic disorder, we collected data on 278 first-degree relatives 41 probands with disorder and 262 control probands. The morbidity risk for was 17.3% in the first group, an additional 7.4% were categorized as having probable disorder. Both rates significantly higher than respective relatives, 1.8% 0.4%. female subjects twice that male subjects. rate generalized anxiety same both groups families. No other psychiatric disorders increased families patients preliminary genetic analysis, tested single major locus multifactorial polygenic transmission models. Neither model excluded by data. We conclude is familial disease affects women frequently men not associated conditions. Its method remains uncertain.