Impact of antibiotic prophylaxis for intrathecal baclofen pump surgery in pediatric patients.

摘要: OBJECT This study explored antibiotic prophylaxis (AP) in pediatric patients undergoing intrathecal baclofen pump (ITBP) surgery and factors associated with perioperative AP compliance clinical guidelines. METHODS Data were obtained from the Pediatric Health Information System. The cohort comprised who underwent ITBP within 3 days of admission, between July 1, 2004, March 31, 2014, a minimum prior screening period follow-up 180 days. Exclusion criteria infection, use 30 and/or missing financial data. Chi-square tests multivariate logistic regressions used to determine guidelines surgeries. RESULTS A total 1,534 met inclusion criteria; 91.5% received 37.6% dual coverage or more. Overall bundled 2 components: 1) administration 2) 24 hours postoperatively, rate was insignificantly higher (22.00%, p = 0.368). Thus, direct relevance practicing clinicians, missed preoperative antibiotics 48% risk adverse complication/infection outcome 6-month time frame. Adjusted hospitalization costs differed significantly (p < 0.001) respect practices: 22.83, 29.10, 37.66 (× 1000 USD) for compliance, antibiotics, prolonged administration, respectively. CONCLUSIONS Significant variation found. Documented value care, showing favorable outcomes. Of most impact outcome, surgical complication/infection. Prolonged hospital compared those overall compliance. Future research is warranted examine practice how outcomes quality, aiming improving delivery care procedures.