Seizure outcome after epilepsy surgery in children and adolescents

摘要: Few epilepsy surgery outcome data are available from series of pediatric patients. We studied seizure in 136 patients who had for intractable at The Cleveland Clinic between January 1990 and June 1996, with a postoperative follow-up 1 to 7.5 years (mean, 3.6 years). Sixty-two children (3 months 12 old time surgery) were compared 74 adolescents (13-20 old). Extratemporal or multilobar resections hemispherectomies similarly frequent among (50%) (44%), but these procedures strongly predominated infancy (90% 0-2 age). remaining temporal resection. Cortical dysplasia low-grade tumor the most common causes hippocampal sclerosis was rare. Seizure-free achieved 69% adolescents, 68% children, 60% infant subgroup, overall; 23 (74%) 31 33 (80%) 41 after resection; 11 (58%) 19 15 (52%) 29 extratemporal 8 (67%) 3 (75%) 4 functional hemispherectomy. more resection (56 72, 78%) than (26 48, 54%; 48 focal lesion on magnetic resonance imaging), (36 44, 82%) versus cortical (16 31, 52%). frequency seizure-free similar infants, comparable results adult series. Most each age, type, causal group free seizures surgery. These suggest that should be considered surgical evaluation whatever age they manifest severe, intractable, disabling localization-related epilepsy.