Lipid biosynthesis in neuron-enriched and glial-enriched fractions of rat brain: sterol formation.

作者: John P. Jones , Robert B. Ramsey , Harold J. Nicholas

DOI: 10.1016/0024-3205(71)90103-2

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摘要: Abstract Glial-enriched fractions were shown to synthesize sterol from [2- 14 C] mevalonic acid. Neuron-enriched incubated with acid, formed much less labeled neutral lipid than did glial-enriched under identical conditions. Sterol esters produced only in the presence of neuron-enriched fractions. Labeled squalene and lanosterol identified fraction incubations.

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