Mass Spectrometry in Biomedical Research

摘要: This book provides a stat-of-the-art coverage of the dramatic extension in application mass spectrometry (MS) to biomedical research that has taken place last few years. been brought about through both developments ionization techniques and improved instrumentation for analyses at high mass. Dr Gaskall together large number eminent innovative researchers MS, whose major motivation is desire solve problems research. Three general areas are covered: a) Analyses labile polar compounds, with emphasis on new sample handling including discussion compound classes such as leukotrienes, nucleic acid constituents drug metabolites; b) mass, discussions peptides, oligonucleotides oligosaccharides presenting recent time-of-flight Fourier transform MS; c) Trace analyses, use tandem MS combined gas liquid chromotography very sensitivity detection analytes steroids, prostaglandins, peptides drugs. Each three sections supplemeted by overviews, authored Gaskill, which provide relevant background material concerning technques, analysers MS.