Enhanced oral insulin delivery via surface hydrophilic modification of chitosan copolymer based self-assembly polyelectrolyte nanocomplex.
作者： Chang Liu , Yongqiang Kou , Xin Zhang , Wei Dong , Hongbo Cheng
DOI: 10.1016/J.IJPHARM.2018.10.068
关键词:
摘要: It is desirable to design nanoparticles for oral insulin delivery that can cross mucus layer and epithelial membrane in the intestine in the meantime. Thus, using chitosan (CS) as the …
sci-hub.se 参考文章(47)
Ryan J. Smith, Rachel W. Beck, Lisa E. Prevette, Impact of molecular weight and degree of conjugation on the thermodynamics of DNA complexation and stability of polyethylenimine-graft-poly(ethylene glycol) copolymers Biophysical Chemistry. ,vol. 203, pp. 12- 21 ,(2015) , 10.1016/J.BPC.2015.04.005
Yuping Huang, Hailong Yu, Liang Guo, Qingrong Huang, Structure and Self-Assembly Properties of a New Chitosan-Based Amphiphile Journal of Physical Chemistry B. ,vol. 114, pp. 7719- 7726 ,(2010) , 10.1021/JP9122216
Irene Pereira de Sousa, Corinna Steiner, Matthias Schmutzler, Matthew D. Wilcox, Gert J. Veldhuis, Jeffrey P. Pearson, Christian W. Huck, Willi Salvenmoser, Andreas Bernkop-Schnürch, Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 97, pp. 273- 279 ,(2015) , 10.1016/J.EJPB.2014.12.024
Shirui Mao, Udo Bakowsky, Anchalee Jintapattanakit, Thomas Kissel, Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin. Journal of Pharmaceutical Sciences. ,vol. 95, pp. 1035- 1048 ,(2006) , 10.1002/JPS.20520
M. Zhang, X.H. Li, Y.D. Gong, N.M. Zhao, X.F. Zhang, Properties and biocompatibility of chitosan films modified by blending with PEG. Biomaterials. ,vol. 23, pp. 2641- 2648 ,(2002) , 10.1016/S0142-9612(01)00403-3
R. Shelma, Chandra P. Sharma, Submicroparticles composed of amphiphilic chitosan derivative for oral insulin and curcumin release applications Colloids and Surfaces B: Biointerfaces. ,vol. 88, pp. 722- 728 ,(2011) , 10.1016/J.COLSURFB.2011.08.007
Linlin Wang, Yujiao Sun, Chenjun Shi, Liang Li, Jian Guan, Xin Zhang, Rui Ni, Xiaopin Duan, Yaping Li, Shirui Mao, Uptake, transport and peroral absorption of fatty glyceride grafted chitosan copolymer-enoxaparin nanocomplexes: influence of glyceride chain length. Acta Biomaterialia. ,vol. 10, pp. 3675- 3685 ,(2014) , 10.1016/J.ACTBIO.2014.05.003
Shirui Mao, Wei Sun, Thomas Kissel, Chitosan-based formulations for delivery of DNA and siRNA Advanced Drug Delivery Reviews. ,vol. 62, pp. 12- 27 ,(2010) , 10.1016/J.ADDR.2009.08.004
Laura M. Ensign, Richard Cone, Justin Hanes, Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Advanced Drug Delivery Reviews. ,vol. 64, pp. 557- 570 ,(2012) , 10.1016/J.ADDR.2011.12.009
Irene Bravo-Osuna, Thierry Schmitz, Andreas Bernkop-Schnürch, Christine Vauthier, Gilles Ponchel, Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles International Journal of Pharmaceutics. ,vol. 316, pp. 170- 175 ,(2006) , 10.1016/J.IJPHARM.2006.02.037