Tendon-bone interface healing using an injectable rhBMP-2-containing collagen gel in a rabbit extra-articular bone tunnel model.
作者： Kwang Won Lee , Jung Soo Lee , Ju Woong Jang , Young Bock Shim , Kwang-Il Lee
DOI: 10.1002/TERM.2041
关键词:
摘要: This study examines the hypothesis that injectable collagen gel can be an effective carrier for recombinant human bone morphogenetic protein‐2 (rhBMP‐2)'s localization to the healing tendon–bone interface. In 36 mature New Zealand White rabbits, the upper long digital extensor tendon was cut and inserted into the proximal tibial bone tunnel. Then a rhBMP‐2‐containing collagen gel was injected into the tendon–bone tunnel interface, using a syringe. Histological and biomechanical assessments of the tendon–bone interface were …
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