Adverse Drug Reaction Identification and Extraction in Social Media: A Scoping Review

摘要: Background: The underreporting of adverse drug reactions (ADRs) through traditional reporting channels is a limitation in the efficiency current pharmacovigilance system. Patients’ experiences with drugs that they report on social media represent new source data may have some value postmarketing safety surveillance. Objective: A scoping review was undertaken to explore breadth evidence about use as knowledge for pharmacovigilance. Methods: Daubt et al’s recommendations reviews were followed. research questions follows: How can be used surveillance? What are available methods extracting data? different ways these We queried PubMed, Embase, and Google Scholar extract relevant articles published before June 2014 no lower date limit. Two pairs reviewers independently screened selected studies proposed two themes review: manual ADR identification (theme 1) automated extraction from 2). Descriptive characteristics collected publications create database 1 2. Results: Of 1032 citations PubMed 11 question. An additional 13 added after further Internet reference lists. Themes 2 explored articles, respectively. Ways approaching identified. Conclusions: This noted multiple identifying target data, them, evaluating quality medical information media. It also showed remaining gaps field. Studies related theme usually failed accurately assess completeness, quality, reliability analyzed Regarding extraction, study generic approach easily adding site or source. Additional required precisely determine role [J Med Res 2015;17(7):e171]