Life-Span and the Inheritance of Longevity of Inbred Mice

摘要: Measures of life-span were obtained for male and female A/J, BALB/cJ, C57BL/6J, DBA/2J inbred mouse strains the six possible hybrid combinations (N equals 500, 10 groups, 25 per group). C57BL/6J mice long lived, while BALB/cJ short with exception mice, which lived as mice. Female two groups a parent longer than males, but significant sex differences not other groups. In general, mode inheritance longevity was overdominant. For second study 400) A/J F1 F2 hybrids it estimated that one genetic factor associated coefficient determination between .48 .79.