Fasciola hepatica infection in cattle and the use of simulation models for endemic areas

摘要: Fasciolosis is a food-borne disease that causes great distress to range of hosts, including humans. The objectives this study were (1) evaluate the liver damage and carcass weight cattle naturally infected with Fasciola hepatica from state Rio Grande do Sul (RS), Brazil, (2) determine distribution adult flukes in 12,236 RS. data these experiments used calculate overall economic loss due F. infection. Eighteen Polled Hereford cows divided into triclabendazole (TbG) hepatica-positive group (FhG). For Experiment 1, generalized linear mixed model revealed statistical difference (49.8 kg) between TbG FhG. Monte Carlo analysis also animals' differences disease. 2, prevalence livers was above 16% (1904/12,236), mostly (20.1%) south-west region Susceptible-infected-recovered (SIR) epidemic evolution infection using high infectivity low recovery rate. Other distinctive scenarios occur RS established different rates infectivity. assessment showed potential US$45 million beef industry RS, an State cost US$90.3 million. These novel findings reveal importance fasciolosis infection, which can cause significant health condition poor animal welfare.