Inferring structures of kinetic intermediates in Ca(2+)-triggered exocytosis.
作者： Meyer B. Jackson
DOI: 10.1016/B978-0-12-385891-7.00008-8
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摘要: Publisher Summary This chapter discusses the inferring structures of kinetic intermediates in Ca2+-triggered exocytosis. The fusion biological membranes proceeds through a series that are generated by structural transitions proteins and deformation lipid bilayers. In membrane during exocytosis, key have been identified subjected to analysis. These used develop hypothetical mechanisms for often invoking explicit intermediates. these posit unique relations between lipids. two requires distortion controlled disruption After being brought very close together, bilayer strained point where they can relax new structure which previously separate become contiguous. Elucidating mechanism is essence an effort characterize distortions search serve as
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