摘要: To the Editor. —In his response to a question from Dr Drucker about fluoxetine (Prozac) and sexual dysfunction, Hollander 1 states that dysfunction with occurs in up 1.9% of patients. Even though Physicians' Desk Reference 2 still carries this figure, is no longer believed reflect true incidence associated other antidepressants. Several studies reported as being much higher, ranging 7.8% 3 34%. 4 Orgasmic antidepressants males has been described these studies. 3,4 Different management approaches have suggested, including oral yohimbine, switching or adding buproprion, addition buspirone, various approaches. For an excellent summary see review by Seagraves. 5 While depression may source case discussed JAMA , patient's