Packaging for a drug delivery microelectromechanical system

Laurence D. Rhines, Prakash Sampath, Francesco DiMeco, H. Christopher Lawson, Betty M. Tyler, Justin Hanes, Alessandro Olivi, Henry Brem, Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma. Neurosurgery. ,vol. 52, pp. 872- 880 ,(2003) , 10.1227/01.NEU.0000053211.39087.D1

Daniel Brat, Henry Brem, Francesco DiMeco, Justin Hanes, Prakash Sampath, Betty M. Tyler, Drew M. Pardoll, Paracrine Immunotherapy with Interleukin-2 and Local Chemotherapy Is Synergistic in the Treatment of Experimental Brain Tumors Cancer Research. ,vol. 59, pp. 2107- 2114 ,(1999)

Justin Hanes, Allen Sills, Zhong Zhao, Kwang Wook Suh, Betty Tyler, Francesco DiMeco, Daniel J. Brat, Michael A. Choti, Kam W. Leong, Drew M. Pardoll, Henry Brem, Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. ,vol. 18, pp. 899- 906 ,(2001) , 10.1023/A:1010963307097

Yawen Li, Mechanical characterization and in vivo operation of an implantable drug delivery MEMS device Massachusetts Institute of Technology. ,(2005)

Rebecca Scheidt Shawgo, In vivo activation and biocompatibility of a MEMS microreservoir drug delivery device Massachusetts Institute of Technology. ,(2004)

John T. Santini, Michael J. Cima, Robert Langer, A controlled-release microchip Nature. ,vol. 397, pp. 335- 338 ,(1999) , 10.1038/16898

Minqiang Bu, Tracy Melvin, Graham J Ensell, James S Wilkinson, Alan GR Evans, None, A new masking technology for deep glass etching and its microfluidic application Sensors and Actuators A-physical. ,vol. 115, pp. 476- 482 ,(2004) , 10.1016/J.SNA.2003.12.013

D. Brennan, P. O’Brien, J. O’Brien, N. Freeman, M. Swann, Development and test of an integrated microsystem for HPLC separation and detection using refractive index measurements Sensors and Actuators B-chemical. ,vol. 103, pp. 184- 189 ,(2004) , 10.1016/J.SNB.2004.04.050

Yong-Ho Kim, Hyun-Woo Lee, Kwang-Woo Lee, Yong-Seog Kim, Formation of barrier ribs for plasma display panels via powder-blasting process: Part II, effects of powder-blasting angle Journal of the American Ceramic Society. ,vol. 87, pp. 348- 351 ,(2004) , 10.1111/J.1551-2916.2004.00348.X

J. Müller, MEMS on silicon for integrated optic metrology and communication systems Microsystem Technologies-micro-and Nanosystems-information Storage and Processing Systems. ,vol. 9, pp. 308- 315 ,(2003) , 10.1007/S00542-002-0238-Y