Improved survival with elective neck dissection in thick early-stage oral squamous cell carcinoma†
作者： Ardalan Ebrahimi , Bruce G. Ashford , Jonathan R. Clark
DOI: 10.1002/HED.21809
关键词:
摘要: Background Management of the node–negative neck in T1 to T2 oral squamous cell carcinoma (SCC) remains controversial. The purpose this study was determine if elective dissection improves outcomes thick primary tumors since reflects current practice most institutions and has not been specifically addressed literature. Methods Retrospective analysis comparing versus observation 153 patients with N0 SCC ≥4 mm thick. Results On multivariable analysis, a significant predictor improved regional control (hazard ratio [HR], 0.1; p < .001), disease-specific (HR, overall survival 0.3; = .001). Regional failure accounted for 22% disease-related deaths group compared 92% arm. Conclusion Elective is associated clinically advantage by reducing risk failure, we support its routine application these patients. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
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