cAMP signaling in Dictyostelium. Complexity of cAMP synthesis, degradation and detection.
作者： Shweta Saran , Marcel E. Meima , Elisa Alvarez‐Curto , Karin E. Weening , Daniel E. Rozen
关键词:
摘要: cAMP plays a pivotal role in control of cell movement, differentiation and response to stress all phases the Dictyostelium life cycle. The multitudinous functions require precise spatial temporal its production, degradation detection. Many novel proteins have recently been identified that critically modulate signal. We focus this review on properties three adenylyl cyclases cAMP-phosphodiesterases are present Dictyostelium, network regulate activity these enzymes. also briefly discuss two modes detection cAMP.
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