Chemoprevention of B-Cell Lymphomas by Inhibition of the Myc Target Spermidine Synthase
作者： TachaZi Plym Forshell , Sara Rimpi , Jonas A. Nilsson
DOI: 10.1158/1940-6207.CAPR-09-0166
关键词:
摘要: The oncogenic transcription factor c-Myc (Myc) is frequently overexpressed in human cancers. Myc known to induce or repress a large set of genes involved cell growth and proliferation, explai ...
aacrjournals.org
sci-hub.se 参考文章(37)
D. Kleine-Kohlbrecher, S. Adhikary, M. Eilers, Mechanisms of transcriptional repression by Myc. Current Topics in Microbiology and Immunology. ,vol. 302, pp. 51- 62 ,(2006) , 10.1007/3-540-32952-8_3
Jagruti H. Patel, Andrey P. Loboda, Michael K. Showe, Louise C. Showe, Steven B. McMahon, Analysis of genomic targets reveals complex functions of MYC Nature Reviews Cancer. ,vol. 4, pp. 562- 568 ,(2004) , 10.1038/NRC1393
Ronald A. Lubet, Gary Kelloff, Ernest T. Hawk, Kendra Tutsch, Carolyn E. Cole, Russell F. Jacoby, Michael A. Newton, Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos. Cancer Research. ,vol. 60, pp. 1864- 1870 ,(2000)
Akira Shirahata, Norio Takahashi, Takanobu Beppu, Harumi Hosoda, Keijiro Samejima, Effects of inhibitors of spermidine synthase and spermine synthase on polyamine synthesis in rat tissues Biochemical Pharmacology. ,vol. 45, pp. 1897- 1903 ,(1993) , 10.1016/0006-2952(93)90449-7
C. Bello-Fernandez, G. Packham, J. L. Cleveland, The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 7804- 7808 ,(1993) , 10.1073/PNAS.90.16.7804
Jonas A Nilsson, John L Cleveland, Myc pathways provoking cell suicide and cancer Oncogene. ,vol. 22, pp. 9007- 9021 ,(2003) , 10.1038/SJ.ONC.1207261
M Li, S Ren, M T Tilli, J A Flaws, R Lubet, C J Grubbs, P A Furth, Chemoprevention of mammary carcinogenesis in a transgenic mouse model by α-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity Oncogene. ,vol. 22, pp. 2568- 2572 ,(2003) , 10.1038/SJ.ONC.1206314
Alexander Pajic, Dimitry Spitkovsky, Barbara Christoph, Bettina Kempkes, Marino Schuhmacher, Martin S. Staege, Markus Brielmeier, Joachim Ellwart, Franz Kohlhuber, Georg W. Bornkamm, Axel Polack, Dirk Eick, Cell cycle activation by c-myc in a Burkitt lymphoma model cell line International Journal of Cancer. ,vol. 87, pp. 787- 793 ,(2000) , 10.1002/1097-0215(20000915)87:6<787::AID-IJC4>3.0.CO;2-6
Nikolaus Seiler, Bernd Knödgen, High-performance liquid chromatographic procedure for the simultaneous determination of the natural polyamines and their monoacetyl derivatives. Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 221, pp. 227- 235 ,(1980) , 10.1016/S0378-4347(00)84307-8
Robert J. Rounbehler, Weimin Li, Mark A. Hall, Chunying Yang, Mohammad Fallahi, John L. Cleveland, Targeting Ornithine Decarboxylase Impairs Development of MYCN-Amplified Neuroblastoma Cancer Research. ,vol. 69, pp. 547- 553 ,(2009) , 10.1158/0008-5472.CAN-08-2968