Age-related reference levels of serum prostate-specific antigen among Taiwanese men without clinical evidence of prostate cancer.
作者： Kuo-Jen Lin , See-Tong Pang , Ying-Hsu Chang , Chun-Te Wu , Kun-Lung Chuang
DOI:
关键词:
摘要: BACKGROUND To determine the normal distribution of serum prostate-specific antigen (PSA) levels in Taiwanese men without clinical evidence prostate cancer. METHODS Between August 2006 and October 2007, healthy undergoing a routine health examination our hospital were recruited into study. All received digital rectal (DRE) PSA determination some transrectal ultrasound (TRUS). Men with DRE findings, < 4.0 ng/ml, between ng/ml 20 negative TRUS or abnormal findings (hypoechoic lesion others) biopsy defined as clinically free RESULTS A total 7803 participants cancer included The median value (95th percentile range) was 0.896 (3.329) for 50-59 years old; 1.151 (5.114) 60-69 1.623 (6.237) 70-79 old 1.754 (6.613) older then 80 years. values correlated age (r = 0.3078, p 0.001). There small changes 95th younger than 50 old, but large increases those CONCLUSIONS These confirm that is directly age, offer more efficient reference screening tests men.
cabdirect.org参考文章(20)
Joseph E. Oesterling, Serum Prostate-Specific Antigen in a Community-Based Population of Healthy Men JAMA. ,vol. 270, pp. 860- 864 ,(1993) , 10.1001/JAMA.1993.03510070082041
Judd W. Moul, Leon Sun, James M. Hotaling, Nicholas J. Fitzsimons, Thomas J. Polascik, Cary N. Robertson, Philipp Dahm, Mitchell S. Anscher, Vladimir Mouraviev, Paul A. Pappas, David M. Albala, Age Adjusted Prostate Specific Antigen and Prostate Specific Antigen Velocity Cut Points in Prostate Cancer Screening The Journal of Urology. ,vol. 177, pp. 499- 504 ,(2007) , 10.1016/J.JURO.2006.09.063
THOMAS J. POLASCIK, JOSEPH E. OESTERLING, ALAN W. PARTIN, PROSTATE SPECIFIC ANTIGEN: A DECADE OF DISCOVERY-WHAT WE HAVE LEARNED AND WHERE WE ARE GOING The Journal of Urology. ,vol. 162, pp. 293- 306 ,(1999) , 10.1016/S0022-5347(05)68543-6
Sang Eun Lee, Cheol Kwak, Moon Soo Park, Chang Ho Lee, Weechang Kang, Seung-June Oh, Ethnic differences in the age-related distribution of serum prostate-specific antigen values: a study in a healthy Korean male population. Urology. ,vol. 56, pp. 1007- 1010 ,(2000) , 10.1016/S0090-4295(00)00837-2
I. M. Thompson, D. P. Ankerst, Prostate-specific antigen in the early detection of prostate cancer Canadian Medical Association Journal. ,vol. 176, pp. 1853- 1858 ,(2007) , 10.1503/CMAJ.060955
Dalin He, Mingzhu Wang, Xingfa Chen, Zhongwei Gao, Hui He, Haiyen E Zhau, Wusheng Wang, Leland W.K Chung, Xunyi Nan, Ethnic differences in distribution of serum prostate-specific antigen: a study in a healthy Chinese male population Urology. ,vol. 63, pp. 722- 726 ,(2004) , 10.1016/J.UROLOGY.2003.10.066
M. Kuriyama, H. Uno, H. Watanabe, H. Yamanaka, Y. Saito, K. Shida, Determination of reference values for total PSA, F/T and PSAD according to prostatic volume in japanese prostate cancer patients with slightly elevated serum PSA levels. Japanese Journal of Clinical Oncology. ,vol. 29, pp. 617- 622 ,(1999) , 10.1093/JJCO/29.12.617
Steven P. Balk, Yoo-Joung Ko, Glenn J. Bubley, Biology of prostate-specific antigen. Journal of Clinical Oncology. ,vol. 21, pp. 383- 391 ,(2003) , 10.1200/JCO.2003.02.083
Ian M Thompson, Donna K Pauler, Phyllis J Goodman, Catherine M Tangen, M Scott Lucia, Howard L Parnes, Lori M Minasian, Leslie G Ford, Scott M Lippman, E David Crawford, John J Crowley, Charles A Coltman Jr, None, Prevalence of Prostate Cancer among Men with a Prostate-Specific Antigen Level ≤4.0 ng per Milliliter New England Journal of Medicine. ,vol. 350, pp. 2239- 2246 ,(2004) , 10.1056/NEJMOA031918
Stacy Loeb, Kimberly A. Roehl, William J. Catalona, Robert B. Nadler, Prostate Specific Antigen Velocity Threshold for Predicting Prostate Cancer in Young Men The Journal of Urology. ,vol. 177, pp. 899- 902 ,(2007) , 10.1016/J.JURO.2006.10.028