Borinic Acid Catalysed Reduction of Tertiary Amides with Hydrosilanes: A Mild and Chemoselective Synthesis of Amines
作者： Aurélien Chardon , Tharwat Mohy El Dine , Rémi Legay , Michaël De Paolis , Jacques Rouden
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摘要: A reduction of various aryl, alkyl, and α,β-unsaturated amides with phenylsilane, catalysed by a borinic acid, is reported. The unprecedented reaction was carried out under very mild conditions led to useful amines. Furthermore, the tolerates variety functional groups. Initial investigations implicated that an intermediate diarylhydroborane involved in mechanism.
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