Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.
作者： Kristina Jonas , Jing Liu , Peter Chien , Michael T. Laub
DOI: 10.1016/J.CELL.2013.06.034
关键词:
摘要: The decision to initiate DNA replication is a critical step in the cell cycle of all organisms. Cells often delay replication in the face of stressful conditions, but the underlying mechanisms …
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