Circulating immune complexes in HIV-infected persons.

摘要: Circulating immune complexes are part of normal defense mechanisms and, therefore, present in various infectious — bacterial and viral diseases. On the other hand, they obviously involved pathogenic mechanisms, e.g., autoimmune diseases or different forms malignancies. Both features recorded acquired immunodeficiency syndrome. Thus, elevated levels antigen-antibody HIV-infected persons had to be expected, were fact demonstrated by several authors. In a cohort study, it was additionally shown that circulating prognostic relevance. After an introduction concerning physiological pathophysiological role general, their involvement course HIV infections is presented discussed. addition, there critical review most commonly applied assay systems for detection quantification complexes.