Aetiologic heterogeneity in pediatric Hodgkin lymphoma? Evidence from the Nordic countries, 1978-2010.

摘要: Background. In epidemiological studies, Hodgkin lymphomas (HL) in children younger than 15 years and HL adolescents adults age 15–35 has traditionally been studied separately, under the assumption that at 0–14 constitute a homogeneous entity. However, continued validity of this research practice affluent settings may be questioned. Specifically, boundary not epidemiologically justified, therefore also questionable clinically. We updated further characterised recent incidence patterns among Nordic children.Material methods. obtained data aged for period 1978–2010 from five nationwide cancer registries. The were analysed by log-linear and/or mixture Poisson regression models.Results. analyses showed statistically significantly decreasing increasing rates older eight years, respectively during study period....