Factor ix fusion proteins and methods of making and using same
作者： Ekta Seth Chhabra , John Kulman , Robert T. Peters , Arjan Van Der Flier , David R. Light
DOI:
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摘要: The present disclosure provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. further discloses methods of making and using the FIX proteins.
lens.org 参考文章(580)
Andrew Lawrence Glasebrook, Alexei Kharitonenkov, Tatiyana Leonidovna Shiyanova, Lisa Janine Hammond, Method for treating diabetes and obesity ,(2002)
Jennifer M. Favaloro, Mirella Ezban Rasmussen, Pablo Valenzuela, Frank Masiarz, Martha Truett, George Kuo, Method and composition for preparation of factor VIIIC ,(1993)
Marc G. Jacquemin, Jean-Marie Saint-Remy, Jean-Guy Gilles, Christian Behrens, Anti-idiotypic antibody which neutralizes the inhibitory activity of an inhibitory antibody directed against the c1 domain of factor viii ,(2007)
Christopher J. Murray, Methods and compositions for grafting functional loops into a protein ,(2003)
Anna-Lisa Smeds, Process for purification of factor VIII ,(1995)
Thomas Nesspor, Kristen Picha, Karyn O'neil, Beverly A. Moore, Audrey E. Baker, Sarah Sague, Jeffrey M. Palmer, Glp-2 mimetibodies, polypeptides, compositions, methods and uses ,(2006)
W S Skinner, M E Adams, G B Quistad, H Kataoka, B J Cesarin, F E Enderlin, D A Schooley, Purification and Characterization of Two Classes of Neurotoxins from the Funnel Web Spider, Agelenopsis aperta Journal of Biological Chemistry. ,vol. 264, pp. 2150- 2155 ,(1989) , 10.1016/S0021-9258(18)94154-2
Shiv Pillai, Abul K. Abbas, Andrew H. Lichtman, Cellular and Molecular Immunology ,(1994)
Henning Ralf Stennicke, Marianne Kjalke, Eva H. Norling Olsen, Jens Jacob Hansen, Bernd Peschke, Henrik Østergaard, Jens Buchardt, Mikael Kofod-Hansen, Factor VIII Molecules With Reduced VWF Binding ,(2011)
Dae-Jin Kim, Gwan-Sun Lee, Chang-Ki Lim, Sung-Min Bae, Young-Min Maehwamaeul Woonam Dream Valley Kim, Se-Chang Kwon, Physiologically active polypeptide conjugate having prolonged in vivo half-life ,(2004)