Calcium and transmitter release.

摘要: Publisher Summary This chapter reviews the experiments on relation between [Ca 2+ ] in and transmitter release at synapses, with an emphasis neuromuscular junction. Then, quantitive models of calcium action, starting simplest adding variables stepwise are discussed, until a model minimum complexity consistent data is reached. The compared to for synapses. In end, implications control spontaneous quantal synaptic facilitation considered. realistic Ca action triggering neurotransmitter takes into account following: that enters following stimulation adds already present resting terminal. Then there cooperative interaction release, n binds receptor trigger quantum, finite number sites. There several reasons believe mechanism eliciting secretion substantially different junction adrenal medulla.