Insecticide cry proteins of bacillus thuringiensis with anti-cancer activity

作者: Gretel Mendoza Almanza , Efraín Arias Bañuelos , Jorge Olmos Soto

DOI:

关键词:

摘要: The invention relates to nucleic acid molecules coding for insecticidal proteins of the Cry family, derived from Bacillus thuringiensis, exhibiting cytotoxic activity against cancer and/or tumour cells humans animals, but not normal cells. also provides and compositions bacteria that exhibit preferably without affecting do any hemolytic activity, nor they belong parasporin group. methods treating preventing metastasis, using thuringiensis.

参考文章(21)
David A. Fischhoff, Frederick J. Perlak, Synthetic plant genes from BT kurstaki and method for preparation ,(1997)
Eiichi Mizuki, Tetsuyuki Akao, Jean-Charles Cote, Yong-Chul Jung, Novel Bacillus thuringiensis strain, crystal gene and crystal protein and uses thereof ,(2004)
Christopher Conlan, Brian A. Stockhoff, Methods of controlling cutworm pests ,(2000)
Cristina Rodriguez-Padilla, Bharat B. Aggarwal, Antiproliferative protein from bacillus thuringiensis var. thuringiensis Official Gazette of the United States Patent and Trademark Office Patents. ,(1996)
David R. Corbin, Charles P. Romano, Plants transformed to express Cry2A δ-endotoxins ,(2002)
Guy A. Cardineau, Steven J. Stelman, Kenneth E. Narva, Plant-optimized genes encoding pesticidal toxins ,(1998)
Linda A. Castle, Willem P. C. Stemmer, Takashi Yamamoto, Optimization of pest resistance genes using dna shuffling ,(1999)
Amy J. Gilmer, Mark J. Rupar, William P. Donovan, Chih-Rei Chu, James A. Baum, Lepidopteran-Active Bacillus Thuringiensis Delta-Endotoxin Compositions and Methods of Use ,(2000)