Biodegradable hydrogel copolymer as drug delivery matrix

摘要: This invention concerns the thermoplastic, biodegradable hydrogel copolymer which is easily degraded and excreted in human body by hydrolysis of intramolecular ester amide bond. The structure present comprises i) hydrophilic swellable soft domain consisting polyethyleneoxide (PEO), ii) hydrophobic, biodegradable, crystallizable non-swellable hard polylactide (PLA), polyglycolide (PGA), polylactideglycolide (PLGA) polycaprolactone (PCL).