Reversible metal ion chelators

作者: Poncho Meisenheimer , Thomas Kirkland , Mark Mcdougall , Min Zhou

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摘要: Provided herein are chelator constructs (e.g., nucleic acid, peptide, peptide etc.) that sequester metal ions Mg 2+ ) under a first set of conditions and fail to or release sequestered second conditions. In particular, acid provided favor secondary tertiary structure formation disfavor the such structures.

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