Gastroparesis: Prevalence, Clinical Significance and Treatment

摘要: The application of novel techniques to quantify gastric motor function and emptying has yielded important insights into the prevalence, pathogenesis clinical sequelae gastroparesis. Both acute chronic gastroparesis occur frequently; solids is delayed in 30% 50% patients with diabetes mellitus, functional dyspepsia gastroesophageal reflux disease. While many experience upper gastrointestinal symptoms that adversely affect quality life, concept are inevitably direct outcome delay now recognized be overly simplistic. In contrast, potential impact on oral drug absorption blood glucose control mellitus probably been underestimated. use prokinetic drugs (cisapride, domperidone, metoclopramide erythromycin) forms mainstay therapy symptomatic gastroparesis, a number pharmacological therapies being evaluated, preliminary studies using pacing show promise.