Risk factors for distant recurrence of hepatocellular carcinoma in the liver after complete coagulation by microwave or radiofrequency ablation.

摘要: BACKGROUND In patients with hepatocellular carcinoma (HCC), recurrences in the distant liver often are observed after curative treatment. Microwave coagulation therapy (MCT) and radiofrequency ablation (RFA) have been developed as less invasive alternatives than surgical resection for small HCCs. In current study, risk factors recurrence of HCC were analyzed whom complete was achieved. METHODS Ninety-two HCCs < 3 cm greatest dimension treated by MCT or RFA percutaneously laparoscopically. Eighty-four achieved without same subsegment primary nodule included this study. Distant 22 patients. Fifteen possible a analyzed. RESULTS When comparing nodules remnant to those recurrence, authors statistically significant difference only serum α-fetoprotein. The recurrence-free survival Kaplan–Meier method. A hepatitis C virus (HCV) infection an etiopathic agent underlying diseases (P 0.005) number 0.05, log-rank test). multivariate stepwise Cox hazard model revealed that HCV independent factors. CONCLUSIONS Patients who had more two accompanied high incidence liver, even when microwave complete. Cancer 2001;91:949–56. © 2001 American Society.