Participation of the subfornical nucleus in hypothalamic-neurohypophyseal axis activation during the early phase of endotoxic shock
作者： Beatriz Carvalho Borges , Maria José Alves da Rocha
DOI: 10.1016/J.NEULET.2006.05.052
关键词:
摘要: During the early phase of endotoxic shock hypothalamus is activated and neurohypophyseal hormone secretion increased. In order to study participation subfornical organ (SFO) in this response we lesioned nucleus determined c-fos expression paraventricular supraoptic nuclei after administration lipopolysaccharides (LPS) rats. LPS significantly increased number cells showing Fos immunoreactivity (p < 0.05) also caused an increase plasma levels vasopressin oxytocin 0.05). SFO lesion reduced LPS-induced We conclude that participates activation hypothalamic-neurohypophyseal axis shock.
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