Antimicrobial and Substantivity Properties of Silver Nanoparticles against Oral Microbiomes Clinically Isolated from Young and Young-Adult Patients

摘要: The dental plaque is an oral microbiome hardly associated to be the etiological agent of caries and periodontal disease which are still considered serious health public problems. Silver nanoparticles (AgNPs) have demonstrated good antimicrobial properties affecting a wide variety microorganisms, including bacteria; however, there no scientific information that has evaluated effect AgNPs against clinical biofilms with disease. aim this study was determine substantivity effects in isolated clinically from patients Sixty-seven young young-adult subjects were sampled through collection subgingival plaque. inhibitory performed standard microbiological assays by triplicate using two sizes particle. Polymerase chain reaction (PCR) assay used identify presence specific bacterial species. All showed for all any age and, generally, gender ( ); effectiveness related particle size, time, ). identified microorganisms S. mutans, sobrinus, sanguinis, gordonii, oralis, P. gingivalis, T. forsythia, intermedia. could as potential control prevention