Mass spectrometry in drug metabolism

摘要: Identification of Drugs and Drug Metabolites.- A study on the metabolism feprazone utilizing mass spectrometry.- some urinary metabolites iopronic acid in human, rat dog.- Metabolite identification by GC-MS: species differences metabolic patterns isopropylbiphenyl.- Structural elucidation an S-oxidized metabolite trithiozine Some 9-hydroxy-19,20-bis-nor-prostanoic acid.- Formation a new amino as intermediate sodium dipropylacetate.- N-acetyl-ss-aryloxyalanines from rats treated with 3-(p-tolyloxy)-1,2-propanediol 3-phenoxy-1,2-propanediol.- Metabolism rat, dog man difenpiramide, anti-inflammatory drug.- Potential drugs propolis.- Quantitation Mass fragmentography (single multiple ion monitoring) drug research.- spectrometric quantification compounds involved pyrazofurin.- spectrometry applied to studies Org GC 94, anti-migraine The measurement urine dihydrodigoxin, cardioinactive digoxin.- Determination dimethylnitrosamine extracts cultures Trichomonas vaginalis, using gas chromatography Blood concentrations monoacylcadaverines schizophrenia.- MHPG, amitriptyline depression: collaborative study.- environmental contaminants: detection chlorophenoxyisobutyrate salicylic GC-MS.- Intermediates Drugs.- Application chemical ionization MS twin-ion intermediates technique analysis reactive metabolism.- Relationship between structure tricyclic drugs: stable epoxide-diol pathway.- Stable Isotope Labelling.- protein chronic-enterocolitis patients effect pharmacological agents Biochemical applications high precision isotope combined chromatography-mass Developments Methodology.- Chemical metabolites.- Field desorption pharmacologically active salts.- Role computers spectrometry: detection, identification, real time chromatograph-mass spectrometer minicomputer system for selected analysis.- Abuse.- Can - influence trends abuse?.- Characterization vivo liver ?1--tetrahydrocannabinol EI CI Detection cannabinoids human blood plasma.- major tetrahydrocannabinol plasma cannabis smokers.- Analysis impurities illicit heroin Screening five commonly used anabolic steroid drugs.- acute intoxication diagnostics: aspects experiences.- Participants.