Performance, ventilation, and oxygen consumption in three different types of exercise test in patients with chronic obstructive lung disease.

摘要: Seventeen patients (six men and 11 women, mean age 66 years) with severe chronic obstructive lung disease (mean FEV1 0.8 (SD 0.3)1) performed three different types of exercise test on four occasions within one week. Three daily doses placebo tablets were given between the third fourth attempt at each test. The tests 12 minute walking test, a fixed rate height paced step cycle ergometer in which work was increased by 10 watts minute. Performance significantly (p less than 0.01) first attempts type (12 min distance 16% 20%); steps climbed 96% (74%); duration cycling 29% (41%]. There trend for increase performance successive to become progressively smaller but this not significant. No effect detected. greatest intersubject range seen (14-126 steps) least (438-1014 m). Significant correlations observed all found results various FVC either weak 0.05) or non-significant. Ventilation (VE) oxygen consumption (VO2) subsequently measured compared eight during Both VE VO2 that achieved greater patient able reach sustain steady state values whereas both reached sustained It is suggested practice any should be made before introduction specific pharmacological treatment even then it may necessary allow effects further repeated testing assessment treatment.