Twin-beams digital holography for 3D tracking and quantitative phase-contrast microscopy in microfluidics.
作者： Pasquale Memmolo , Andrea Finizio , Melania Paturzo , Lisa Miccio , Pietro Ferraro
DOI: 10.1364/OE.19.025833
关键词:
摘要: We report on a compact twin-beam interferometer that can be adopted as flexible diagnostic tool in microfluidic platforms with twofold functionality. The novel configuration allows 3D tracking of micro-particles and, at same time, simultaneously furnish Quantitative Phase-contrast maps tracked micro-objects by interference microscopy, without changing the configuration. Experimental demonstration is given for vitro cells environment.
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Alexander Rohrbach, Holger Kress, Ernst H. K. Stelzer, Three-dimensional tracking of small spheres in focused laser beams: influence of the detection angular aperture. Optics Letters. ,vol. 28, pp. 411- 413 ,(2003) , 10.1364/OL.28.000411
Oliver Otto, Fabian Czerwinski, Joanne L. Gornall, Gunter Stober, Lene B. Oddershede, Ralf Seidel, Ulrich F. Keyser, Real-time particle tracking at 10,000 fps using optical fiber illumination Optics Express. ,vol. 18, pp. 22722- 22733 ,(2010) , 10.1364/OE.18.022722
YongKeun Park, Gabriel Popescu, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, Fresnel particle tracing in three dimensions using diffraction phase microscopy Optics Letters. ,vol. 32, pp. 811- 813 ,(2007) , 10.1364/OL.32.000811
Ahmed El Mallahi, Frank Dubois, Dependency and precision of the refocusing criterion based on amplitude analysis in digital holographic microscopy. Optics Express. ,vol. 19, pp. 6684- 6698 ,(2011) , 10.1364/OE.19.006684
Michael J. Mlodzianoski, Manuel F. Juette, Glen L. Beane, Joerg Bewersdorf, Experimental characterization of 3D localization techniques for particle-tracking and super-resolution microscopy. Optics Express. ,vol. 17, pp. 8264- 8277 ,(2009) , 10.1364/OE.17.008264
Björn Kemper, Patrik Langehanenberg, Alexander Höink, Gert von Bally, Falk Wottowah, Stefan Schinkinger, Jochen Guck, Josef Käs, Ilona Bredebusch, Jürgen Schnekenburger, Karin Schütze, Monitoring of laser micromanipulated optically trapped cells by digital holographic microscopy Journal of Biophotonics. ,vol. 3, pp. 425- 431 ,(2010) , 10.1002/JBIO.201000035
Demetri Psaltis, Stephen R. Quake, Changhuei Yang, Developing optofluidic technology through the fusion of microfluidics and optics Nature. ,vol. 442, pp. 381- 386 ,(2006) , 10.1038/NATURE05060
Donald B. Conkey, Rahul P. Trivedi, Sri Rama Prasanna Pavani, Ivan I. Smalyukh, Rafael Piestun, Three-dimensional parallel particle manipulation and tracking by integrating holographic optical tweezers and engineered point spread functions Optics Express. ,vol. 19, pp. 3835- 3842 ,(2011) , 10.1364/OE.19.003835
Robert Kiss, Christine Decaestecker, Frank Dubois, Catherine Yourassowsky, Olivier Monnom, Jean-Claude Legros, Olivier Debeir, Philippe Van Ham, Digital holographic microscopy for the three-dimensional dynamic analysis of in vitro cancer cell migration Journal of Biomedical Optics. ,vol. 11, pp. 054032- ,(2006) , 10.1117/1.2357174
G. Coppola, G. Di Caprio, M. Gioffré, R. Puglisi, D. Balduzzi, A. Galli, L. Miccio, M. Paturzo, S. Grilli, A. Finizio, P. Ferraro, Digital self-referencing quantitative phase microscopy by wavefront folding in holographic image reconstruction Optics Letters. ,vol. 35, pp. 3390- 3392 ,(2010) , 10.1364/OL.35.003390