Medical Treatment of Alcohol Dependence: A Systematic Review
作者： Peter M Miller , Sarah W Book , Scott H Stewart , None
DOI: 10.2190/PM.42.3.B
关键词:
摘要: Objective:To summarize published data on pharmacologic treatments for alcohol dependence alone and in combination with brief psychosocial therapies that may be feasible primary care specialty medical settings.Methods:We conducted electronic searches of original research articles reviews MEDLINE, SCOPUS, CINAHL, Embase, PsychINFO. In addition, hand reference lists review articles, supplemental internet references contacts experts the field were conducted. Randomized controlled studies between January 1960 August 2010 met our inclusion/exclusion criteria included.Results:A total 85 studies, representing 18,937 subjects, inclusion. The evidence base oral naltrexone (6% more days abstinent than placebo largest study) topiramate (prescribed off-label) (e.g., 26.2% a recent is positive but modest. Acamprosate shows modest efficacy rece...
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