Tourette syndrome as a motor disorder revisited - Evidence from action coding.

摘要: Abstract Because tics are the defining clinical feature of Tourette syndrome, it is conceptualized predominantly as a motor disorder. There some evidence though suggesting that neural basis syndrome related to perception–action processing and binding between perception action. However, processes have not been examined in domain these patients. If particularly but within system, this would further corroborate predominantly, or solely, Here, we studied N = 22 patients N = 24 healthy controls using an established action coding paradigm derived from Theory Event Coding framework concomitant EEG-recording addressing planned postponed, interleaved immediate reaction with different levels overlap elements. Behavioral performance during was normal syndrome. Response locked lateralized readiness potentials reflecting execution were larger only simple conditions. pre-motor including response preparation configuration reflected by stimulus-locked normal. This supported Bayesian data analysis providing for null hypothesis. The finding integrating action-related elements prior suggests solely Considering other recent evidence, show changes “binding” specific integration coding.