Systematic identification of genomic markers of drug sensitivity in cancer cells

作者: Mathew J Garnett , Elena J Edelman , Sonja J Heidorn , Chris D Greenman , Anahita Dastur

DOI: 10.1038/NATURE11005

关键词:

摘要: … of genomic diversity in cancer and to identify rare mutant subsets with altered drug sensitivity… rare types of adult and childhood cancers of epithelial, mesenchymal and haematopoietic …

参考文章(39)
Scudiero Da, Paull Kd, Abbott Bj, Shoemaker Rh, Monks A, Mayo Jg, Alley Mc, McLemore Tl, Boyd Mr, Fine Dl, Development of human tumor cell line panels for use in disease-oriented drug screening. Progress in Clinical and Biological Research. ,vol. 276, pp. 265- ,(1988)
U. McDermott, S. V. Sharma, L. Dowell, P. Greninger, C. Montagut, J. Lamb, H. Archibald, R. Raudales, A. Tam, D. Lee, S. M. Rothenberg, J. G. Supko, R. Sordella, L. E. Ulkus, A. J. Iafrate, S. Maheswaran, C. N. Njauw, H. Tsao, L. Drew, J. H. Hanke, X.-J. Ma, M. G. Erlander, N. S. Gray, D. A. Haber, J. Settleman, Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 19936- 19941 ,(2007) , 10.1073/PNAS.0707498104
Hiroshi Hanafusa, Satoru Torii, Takayuki Yasunaga, Eisuke Nishida, Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway Nature Cell Biology. ,vol. 4, pp. 850- 858 ,(2002) , 10.1038/NCB867
Donna M. Weber, Christine Chen, Ruben Niesvizky, Michael Wang, Andrew Belch, Edward A. Stadtmauer, David Siegel, Ivan Borrello, S. Vincent Rajkumar, Asher Alban Chanan-Khan, Sagar Lonial, Zhinuan Yu, John Patin, Marta Olesnyckyj, Jerome B. Zeldis, Robert D. Knight, Lenalidomide plus Dexamethasone for Relapsed Multiple Myeloma in North America The New England Journal of Medicine. ,vol. 357, pp. 2133- 2142 ,(2007) , 10.1056/NEJMOA070596
Wenchang Guo, Philip Reigan, David Siegel, Joseph Zirrolli, Daniel Gustafson, David Ross, Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition. Cancer Research. ,vol. 65, pp. 10006- 10015 ,(2005) , 10.1158/0008-5472.CAN-05-2029
Nicolò Riggi, Luisa Cironi, Paolo Provero, Mario-Luca Suvà, Jean-Christophe Stehle, Karine Baumer, Louis Guillou, Ivan Stamenkovic, Expression of the FUS-CHOP Fusion Protein in Primary Mesenchymal Progenitor Cells Gives Rise to a Model of Myxoid Liposarcoma Cancer Research. ,vol. 66, pp. 7016- 7023 ,(2006) , 10.1158/0008-5472.CAN-05-3979
Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A Margolin, Sungjoon Kim, Christopher J Wilson, Joseph Lehár, Gregory V Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray, Michael F Berger, John E Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jané-Valbuena, Felipa A Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H Engels, Jill Cheng, Guoying K Yu, Jianjun Yu, Peter Aspesi, Melanie De Silva, Kalpana Jagtap, Michael D Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C Onofrio, Ted Liefeld, Laura MacConaill, Wendy Winckler, Michael Reich, Nanxin Li, Jill P Mesirov, Stacey B Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E Myer, Barbara L Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L Harris, Matthew Meyerson, Todd R Golub, Michael P Morrissey, William R Sellers, Robert Schlegel, Levi A Garraway, None, The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Nature. ,vol. 483, pp. 603- 607 ,(2012) , 10.1038/NATURE11003
Lin Deng, Gang Li, Ronghui Li, Qinglin Liu, Qiaowei He, Jian Zhang, None, Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo. Cancer Biology & Therapy. ,vol. 9, pp. 875- 884 ,(2010) , 10.4161/CBT.9.11.11634
Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, Sarada Gurubhagavatula, Ross A. Okimoto, Brian W. Brannigan, Patricia L. Harris, Sara M. Haserlat, Jeffrey G. Supko, Frank G. Haluska, David N. Louis, David C. Christiani, Jeff Settleman, Daniel A. Haber, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib The New England Journal of Medicine. ,vol. 350, pp. 2129- 2139 ,(2004) , 10.1056/NEJMOA040938
Sara A. Byron, Michael G. Gartside, Candice L. Wellens, Mary A. Mallon, Jack B. Keenan, Matthew A. Powell, Paul J. Goodfellow, Pamela M. Pollock, Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation Cancer Research. ,vol. 68, pp. 6902- 6907 ,(2008) , 10.1158/0008-5472.CAN-08-0770