Acute Recovery and Delayed Changes in Tissue Following Transient Cerebral Hypoxia-Ischemia:Impedance,Electron Microscopy and MR Imaging Studies in Rats

摘要: A transient episode of cerebral hypoxia-ischemia will produce biochemical and cellular changes that may be followed by a delayed cell death. Magnetic resonance (MR) imaging techniques have demonstrated despite normalization images post reperfusion, secondary or return hyperintense areas in the T2 diffusion weighted (DW) can appear several hours after end hypoxic-ischemic insult [1, 2]. Reductions extracellular space swelling are known to occur during ischemia considered underly some these MR changes. How well recover upon reperfusion is not known. Presently, we examine pre, rats at two different ages because MR-imaging differ between them [2].