Value of duplex and color doppler ultrasonography in the evaluation of orbital vascular flow and resistance in sickle cell disease.

作者: Kairgeldy Aikimbaev , Birol Guvenc , Abdullah Canataroglu , Hatice Canataroglu , Fikri Baslamisli

DOI: 10.1002/AJH.1100

关键词:

摘要: The aim of the present study was to assess and compare orbital retinal vascular flow dynamics resistance in patients with homozygous sickle cell disease controls by means duplex color Doppler ultrasonography. Forty-six (SCD) 20 healthy subjects were included study. None had objective signs ocular involvement. Duplex ultrasonography ophthalmic, short posterior ciliary, central arterial flows both eyes performed peak systolic velocity (PSFV), end-diastolic (EDFV), mean (MFV) through entire cardiac cycle further calculation resistive indices (RI) pulsatility (PI). Ophthalmic velocities significantly increased SCD than (P < 0.0001). Blood artery found be reduced 0.0001) while RI PI values markedly higher 0.02 P 0.03) compared controls. Reduction increase related hemoglobin hematocrit levels, red blood count, corpuscular volume 0.009, 0.01, 0.02, 0.04, respectively). In conclusion, who no involvement allowed detection enhancement ophthalmic velocities, resistance, which are associated haematological features.

参考文章(34)
Juan E. Grunwald, Alexander J. Brucker, Joan Baine, Charles E. Riva, Total retinal volumetric blood flow rate in diabetic patients with poor glycemic control. Investigative Ophthalmology & Visual Science. ,vol. 33, pp. 356- 363 ,(1992)
J E Grunwald, B L Petrig, F Robinson, S H Sinclair, C E Riva, Retinal blood flow autoregulation in response to an acute increase in blood pressure. Investigative Ophthalmology & Visual Science. ,vol. 27, pp. 722- 726 ,(1986)
J. E. Grunwald, C. E. Riva, S. H. Sinclair, A. J. Brucker, B. L. Petrig, Laser Doppler velocimetry study of retinal circulation in diabetes mellitus. Archives of Ophthalmology. ,vol. 104, pp. 991- 996 ,(1986) , 10.1001/ARCHOPHT.1986.01050190049038
V. Patel, S. Rassam, R. Newsom, J. Wiek, E. Kohner, Retinal blood flow in diabetic retinopathy. BMJ. ,vol. 305, pp. 678- 683 ,(1992) , 10.1136/BMJ.305.6855.678
J.M.A. Teixeira, K. Duncan, E. Letsky, N.M. Fisk, Middle cerebral artery peak systolic velocity in the prediction of fetal anemia Ultrasound in Obstetrics and Gynecology. ,vol. 15, pp. 205- 208 ,(2000) , 10.1046/J.1469-0705.2000.00070.X
Graham R. Serjeant, The Conjunctival Sign in Sickle Cell Anemia JAMA. ,vol. 219, pp. 1428- 1431 ,(1972) , 10.1001/JAMA.1972.03190370020005
Krishan C. Nagpal, Morton F. Goldberg, Maurice F. Rabb, Ocular manifestations of sickle hemoglobinopathies Survey of Ophthalmology. ,vol. 21, pp. 391- 411 ,(1977) , 10.1016/0039-6257(77)90042-X
D. I. Bulas, A. M. Jones, J. J. Seibert, C. Driscoll, R. O'Donnell, R. J. Adams, Transcranial Doppler (TCD) screening for stroke prevention in sickle cell anemia: pitfalls in technique variation. Pediatric Radiology. ,vol. 30, pp. 733- 738 ,(2000) , 10.1007/S002470000317
Robert J Adams, Virgil C McKie, Don Brambilla, Elizabeth Carl, Dianne Gallagher, Fenwick T Nichols, Steve Roach, Miguel Abboud, Brian Berman, Catherine Driscoll, Beatrice Files, Lewis Hsu, Anne Hurlet, Scott Miller, Nancy Olivieri, Charles Pegelow, Charles Scher, Elliott Vichinsky, Winfred Wang, Gerald Woods, Abdullah Kutlar, Elizabeth Wright, Susan Hagner, Foss Tighe, Jonathan Lewin, Joel Cure, Robert A Zimmerman, Myron A Waclawiw, Stroke Prevention Trial in Sickle Cell Anemia Controlled Clinical Trials. ,vol. 19, pp. 110- 129 ,(1998) , 10.1016/S0197-2456(97)00099-8
S J Erickson, L E Hendrix, B M Massaro, G J Harris, M F Lewandowski, W D Foley, T L Lawson, Color Doppler flow imaging of the normal and abnormal orbit. Radiology. ,vol. 173, pp. 511- 516 ,(1989) , 10.1148/RADIOLOGY.173.2.2678264