Two new labdane-type diterpenes from the wood of Cunninghamia konishii
作者： Chi-I Chang , Yen-Cheng Li , Yong-Han Hong , Wei-Yi Cheng , Che-Yi Chao
DOI: 10.1016/J.PHYTOL.2013.10.008
关键词:
摘要: Our preliminary pharmaceutical screening revealed that the methanol extract of wood Cunninghamia konishii possessed significant anti-inflammatory activity. Further phytochemical investigation led to isolation two new labdane-type diterpenoids, (12S,13S)-12,13-epoxy-8(17),14-labdadien-18-ol (1) and (12S,13S)-12,13-epoxy-8(17),14-labdadien-19-oic acid (2), along with four known (12R,13R)-12,13-epoxy-labda-8(17),14-dien-19-oic (3), 12,13-dihydroxylabda-8(17),14-dien-19-oic (4), sclareol (5), 13-epi-sclareol (6). Their structures were determined by analysis spectroscopic data comparison analogues.
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