Microcarcinoma of the thyroid gland: the Gustave-Roussy Institute experience.

摘要: Background Patients with thyroid microcarcinoma (TMC) have favorable long term prognoses. However, recurrences in the neck and distant metastases been reported. The authors investigated independent factors associated recurrence an effort to define therapeutic guidelines. Methods Two hundred eighty-one patients (207 females, 74 males; mean age, 41.9 years) a differentiated carcinoma Results TMC diagnosis was incidental 189 patients, were first manifestation of disease other 92 patients. Therapy included near-total thyroidectomy for 195 lymph node dissection 195, administration radioiodine 124. Eleven (3.9%) observed 4.3+/-2.7 years (mean +/- standard deviation) after initial treatment: all had locoregional (4 bed 7 nodes), one these local lung metastases. Multivariate analysis showed that two parameters significantly influenced recurrence, namely, number histologic foci (P Conclusions rate appears be low (3.9%). In authors' view, loboisthmusectomy is treatment choice when only focus cancer found histologically, total optimal multiple foci.