Stammzellentherapie — Frischzellentherapie der Zukunft?

作者: Alwin Krämer , Anthony D. Ho

DOI: 10.1007/978-3-540-48562-9_11

关键词:

摘要: Wunderwaffe der Medizin, Multitalente, Alleskonner — so lauten die gebrauchlichen Umschreibungen fur Stammzellen. Es besteht Hoffnung, dass kunftig Volkskrankheiten wie Morbus Parkinson, Herzinfarkt, Diabetes oder gar Alzheimer mit Stammzellen geheilt werden konnen. Vor sieben Jahren wurden Verfahren zur Kultur von aus menschlichen Embryonen etabliert. Diese offneten vollig neue Perspektiven Gewebezucht und Organersatz. Fast gleichzeitig haben viele Forscher in Tiermodellen Hinweise dafur gefunden, Stammzellen, erwachsenen Individuen gewonnen werden, genauso leistungsfahig sind.

参考文章(42)
T. Hunziker, Autologer kultivierter Hautersatz Hautarzt. ,vol. 55, pp. 1077- 1086 ,(2004) , 10.1007/S00105-004-0830-4
Lee M. Silver, Gail R. Martin, Sidney Strickland, Teratocarcinoma stem cells Cold Spring Harbor Laboratory. ,(1983)
Brian J. P. Huntly, D. Gary Gilliland, Leukaemia stem cells and the evolution of cancer-stem-cell research Nature Reviews Cancer. ,vol. 5, pp. 311- 321 ,(2005) , 10.1038/NRC1592
Eric Lagasse, Heather Connors, Muhsen Al-Dhalimy, Michael Reitsma, Monika Dohse, Linda Osborne, Xin Wang, Milton Finegold, Irving L. Weissman, Markus Grompe, Purified hematopoietic stem cells can differentiate into hepatocytes in vivo Nature Medicine. ,vol. 6, pp. 1229- 1234 ,(2000) , 10.1038/81326
A.A. Kocher, M.D. Schuster, M.J. Szabolcs, S. Takuma, D. Burkhoff, J. Wang, S. Homma, N.M. Edwards, S. Itescu, Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function Nature Medicine. ,vol. 7, pp. 430- 436 ,(2001) , 10.1038/86498
Eva Mezey, Karen J Chandross, Gyongyi Harta, Richard A Maki, Scott R McKercher, Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow Science. ,vol. 290, pp. 1779- 1782 ,(2000) , 10.1126/SCIENCE.290.5497.1779
Donald Orlic, Jan Kajstura, Stefano Chimenti, Igor Jakoniuk, Stacie M. Anderson, Baosheng Li, James Pickel, Ronald McKay, Bernardo Nadal-Ginard, David M. Bodine, Annarosa Leri, Piero Anversa, Bone marrow cells regenerate infarcted myocardium Nature. ,vol. 410, pp. 701- 705 ,(2001) , 10.1038/35070587
Neil D. Theise, Sunil Badve, Romil Saxena, Octavian Henegariu, Stewart Sell, James M. Crawford, Diane S. Krause, Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation Hepatology. ,vol. 31, pp. 235- 240 ,(2000) , 10.1002/HEP.510310135
Morayma Reyes, Troy Lund, Todd Lenvik, Dean Aguiar, Lisa Koodie, Catherine M. Verfaillie, Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells Blood. ,vol. 98, pp. 2615- 2625 ,(2001) , 10.1182/BLOOD.V98.9.2615
BE Petersen, WC Bowen, KD Patrene, WM Mars, AK Sullivan, Net al Murase, SS Boggs, JS Greenberger, JP Goff, Bone Marrow as a Potential Source of Hepatic Oval Cells Science. ,vol. 284, pp. 1168- 1170 ,(1999) , 10.1126/SCIENCE.284.5417.1168