Electrochemical Gold(III) Sensor with High Sensitivity and Tunable Dynamic Range
作者： Yao Wu , Rebecca Y. Lai
DOI: 10.1021/ACS.ANALCHEM.5B03868
关键词:
摘要: We report the design and fabrication of a sensitive, specific, selective electrochemical ion (E-ION) sensor for detection Au(III). The signaling mechanism is based on interactions between Au(III) adenine; formation these complexes rigidifies methylene blue (MB)-modified oligoadenine probes, resulting in concentration-dependent reduction MB signal. dynamic range can be tuned by simply changing length DNA probe (six (A6) or 12 (A12) adenines). Independent length, both sensors have demonstrated to with limits 50 20 nM A6 A12 sensors, respectively. With further optimization, this sensing strategy may offer promising approach analyzing
acs.org
elsevier.com
sci-hub.se 参考文章(53)
Attila Yildiz, Handan Gülce, Muammer Kavanoz, Anodic Stripping Voltammetric Determination of Gold on a Polyvinylferrocene Coated Glassy Carbon Electrode Turkish Journal of Chemistry. ,vol. 28, pp. 287- 298 ,(2004)
Yao Wu, Rebecca Y. Lai, Development of a “signal-on” electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection Chemical Communications. ,vol. 49, pp. 3422- 3424 ,(2013) , 10.1039/C3CC41281D
Yu Xiang, Aijun Tong, Yi Lu, None, Abasic Site-Containing DNAzyme and Aptamer for Label-Free Fluorescent Detection of Pb2+ and Adenosine with High Sensitivity, Selectivity, and Tunable Dynamic Range Journal of the American Chemical Society. ,vol. 131, pp. 15352- 15357 ,(2009) , 10.1021/JA905854A
Liang Ning, Yang Liyuan, Dai Jirui, Pang Xugui, Heavy Metal Pollution in Surface Water of Linglong Gold Mining Area, China Procedia environmental sciences. ,vol. 10, pp. 914- 917 ,(2011) , 10.1016/J.PROENV.2011.09.146
Jung Ho Do, Ha Na Kim, Juyoung Yoon, Jong Seung Kim, Hae-Jo Kim, A Rationally Designed Fluorescence Turn-On Probe for the Gold(III) Ion Organic Letters. ,vol. 12, pp. 932- 934 ,(2010) , 10.1021/OL902860F
Pratik K. Sen, Nasimul Gani, Jayanta K. Midya, Biswajit Pal, Kinetics and mechanism of the reduction of gold(III) by glycine in acetate buffer Transition Metal Chemistry. ,vol. 33, pp. 229- 236 ,(2008) , 10.1007/S11243-007-9019-X
Elicia L.S. Wong, Edith Chow, J. Justin Gooding, The electrochemical detection of cadmium using surface-immobilized DNA Electrochemistry Communications. ,vol. 9, pp. 845- 849 ,(2007) , 10.1016/J.ELECOM.2006.11.018
Ryan J. White, Kevin W. Plaxco, Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors. Analytical Chemistry. ,vol. 82, pp. 73- 76 ,(2010) , 10.1021/AC902595F
Angela Casini, Christian Hartinger, Chiara Gabbiani, Enrico Mini, Paul J. Dyson, Bernard K. Keppler, Luigi Messori, Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action. Journal of Inorganic Biochemistry. ,vol. 102, pp. 564- 575 ,(2008) , 10.1016/J.JINORGBIO.2007.11.003
Rebecca Y. Lai, Bryce Walker, Kent Stormberg, Anita J. Zaitouna, Weiwei Yang, Electrochemical techniques for characterization of stem-loop probe and linear probe-based DNA sensors Methods. ,vol. 64, pp. 267- 275 ,(2013) , 10.1016/J.YMETH.2013.07.041