Modeling a Tumor Growth with Piecewise Constant Arguments

作者: F. Bozkurt

DOI: 10.1155/2013/841764

关键词:

摘要: This study is based on an early brain tumor growth that modeled as a hybrid system such (A): , where the parameters and denote positive numbers, are negative numbers integer part of . Equation (A) explains growth, embedded to show drug effect rate causes by immune population. Using (A), we have constructed two models growth: one other population model at low density incorporating Allee function time To consider global behavior investigate discrete solutions (A). Examination characterization stability shows increase decreases local equilibrium point The simulations give detailed description with without effect.

参考文章(31)
Daniel J Brat, Balveen Kaur, Erwin G Van Meir, None, Genetic modulation of hypoxia induced gene expression and angiogenesis relevance to brain tumors Frontiers in Bioscience. ,vol. 8, pp. d100- 116 ,(2003) , 10.2741/942
Esther Hulleman, Kristian Helin, Molecular Mechanisms in Gliomagenesis Advances in Cancer Research. ,vol. 94, pp. 1- 27 ,(2005) , 10.1016/S0065-230X(05)94001-3
E. Chatterjee, E.A. Grove, Y. Kostrov, G. Ladas, On the Trichotomy Character of Journal of Difference Equations and Applications. ,vol. 9, pp. 1113- 1128 ,(2003) , 10.1080/1023619031000146850
Kazuya Uesugi, Yoshiaki Muroya, Emiko Ishiwata, On the global attractivity for a logistic equation with piecewise constant arguments Journal of Mathematical Analysis and Applications. ,vol. 294, pp. 560- 580 ,(2004) , 10.1016/J.JMAA.2004.02.031
Yoshiaki Muroya, Persistence, contractivity and global stability in logistic equations with piecewise constant delays Journal of Mathematical Analysis and Applications. ,vol. 270, pp. 602- 635 ,(2002) , 10.1016/S0022-247X(02)00095-1
Joseph W.-H. SO, J. S. YU, Global stability in a logistic equation with piecewise constant arguments Hokkaido Mathematical Journal. ,vol. 24, pp. 269- 286 ,(1995) , 10.14492/HOKMJ/1380892595
Thomas Stephan, Christian Wissel, Stochastic extinction models discrete in time Ecological Modelling. pp. 183- 192 ,(1994) , 10.1016/0304-3800(94)90017-5
Robert M. May, George F. Oster, Bifurcations and Dynamic Complexity in Simple Ecological Models The American Naturalist. ,vol. 110, pp. 573- 599 ,(1976) , 10.1086/283092