Computing and visualizing electric potentials and current pathways in the thorax.

作者: Quan Ni , Robert S. MacLeod , Bonnie B. Punske , Bruno Taccardi

DOI: 10.1054/JELC.2000.20309

关键词:

摘要: The long-term goal of electrocardiography is to relate electric potentials on the body surface with activities in heart. Many previously reported studies have focused direct links between heart and potentials. goals this study were first validate computational methods determining volume currents high-resolution experimental measurements then use interactive visualization thoracic understand features electrocardiographic fields from measured cardiac sources. We developed both simulation based a realistic shaped torso phantom containing an isolated, perfused dog Interventions included atrial pacing, single pacing simultaneously at multiple locations ventricles. Simulated closely matched torso-tank preparation (mean correlation coefficients 0.95). Simulation further provided means estimating current field computed local geometric conductive properties medium. Applying these techniques under variety conditions, we demonstrated that can provide many insights into relationship potential Specifically, shown factors including source configuration location play important role what extent activity directly visible electrocardiogram. computation toolkit explore associated events may new electrocardiology.

参考文章(28)
William D. Gropp, Satish Balay, Modern Software Tools in Scientific Computing ,(1994)
Steven G. Parker, David M. Weinstein, Christopher R. Johnson, The SCIRun Computational Steering Software System Modern Software Tools for Scientific Computing. pp. 5- 44 ,(1997) , 10.1007/978-1-4612-1986-6_1
Roger P. Holland, Harold Brooks, TQ-ST segment mapping: critical review and analysis of current concepts. American Journal of Cardiology. ,vol. 40, pp. 110- 129 ,(1977) , 10.1016/0002-9149(77)90109-6
B Taccardi, E Macchi, R L Lux, P R Ershler, S Spaggiari, S Baruffi, Y Vyhmeister, Effect of myocardial fiber direction on epicardial potentials. Circulation. ,vol. 90, pp. 3076- 3090 ,(1994) , 10.1161/01.CIR.90.6.3076
DIRK DURRER, R. TH. VAN DAM, G. E. FREUD, M. J. JANSE, F. L. MEIJLER, R. C. ARZBAECHER, Total Excitation of the Isolated Human Heart Circulation. ,vol. 41, pp. 899- 912 ,(1970) , 10.1161/01.CIR.41.6.899
L S Green, B Taccardi, P R Ershler, R L Lux, Epicardial potential mapping. Effects of conducting media on isopotential and isochrone distributions. Circulation. ,vol. 84, pp. 2513- 2521 ,(1991) , 10.1161/01.CIR.84.6.2513
R.S. MacLeod, C.R. Johnson, M.A. Matheson, Visualization blackboard-visualizing bioelectric fields IEEE Computer Graphics and Applications. ,vol. 13, pp. 10- 12 ,(1993) , 10.1109/38.219444
Roger C. Barr, Maynard Ramsey, Madison S. Spach, Relating Epicardial to Body Surface Potential Distributions by Means of Transfer Coefficients Based on Geometry Measurements IEEE Transactions on Biomedical Engineering. ,vol. BME-24, pp. 1- 11 ,(1977) , 10.1109/TBME.1977.326201
Christopher R. Johnson, Computational and numerical methods for bioelectric field problems Critical Reviews in Biomedical Engineering. ,vol. 25, pp. 1- 81 ,(1997) , 10.1615/CRITREVBIOMEDENG.V25.I1.10