Bone mineral density in children and adolescents with systemic lupus erythematosus, juvenile dermatomyositis, and systemic vasculitis: relationship to disease duration, cumulative corticosteroid dose, calcium intake, and exercise.

作者: Khayriah A Alsufyani , Olivia Ortiz-Alvarez , David A Cabral , Lori B Tucker , Ross E Petty

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摘要: OBJECTIVE: To describe the frequency of abnormal bone mineralization in a population children with juvenile systemic lupus erythematosus (JSLE), dermatomyositis (JDM), and vasculitis; to investigate relationship mineral density (BMD) cumulative corticosteroid dose, disease duration, Tanner stage, calcium intake, exercise these patients. METHODS: A retrospective chart review attending pediatric rheumatology clinic at British Columbia9s Children9s Hospital was conducted obtain demographic data (sex, ethnicity, mean daily dose). All patients had least one BMD measurement by dual energy x-ray absorptiometry (DEXA) lumbar spine, hip, total body. expressed as g/cm2 Z scores; an score defined

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