Neuronal cell injury in patients after cardiopulmonary resuscitation: evaluation by diffusion-weighted imaging and magnetic resonance spectroscopy.

作者: Hitoshi Kano , Kiyohiro Houkin , Kuniaki Harada , Izumi Koyanagi , Satoshi Nara

DOI: 10.1007/S10143-005-0408-3

关键词:

摘要: Neuronal cell injury after global cerebral ischemic insult is not well understood in humans. We performed serial examination of diffusion-weighted imaging and magnetic resonance spectroscopy three patients cardiopulmonary resuscitation. The presence the signal for lactate acute stage resuscitation was closely correlated to irreversible damage. In addition, high intensity image also predicted a poor outcome. Lesions that were positive these factors led serious brain damage subacute chronic stages. results indicated resuscitation, an extremely useful modality estimate prognosis patients, which always easy using conventional methods.

参考文章(13)
M.V. Lareu, A. Alvarez-Prechous, C. Pardiñas, L. Concheiro, A. Carracedo, Genetic markers in alcoholic liver cirrhosis. Human Heredity. ,vol. 42, pp. 235- 241 ,(1992) , 10.1159/000154076
Hajime Arai, Janet V. Passonneau, W. David Lust, Energy metabolism in delayed neuronal death of CA1 neurons of the hippocampus following transient ischemia in the gerbil Metabolic Brain Disease. ,vol. 1, pp. 263- 278 ,(1986) , 10.1007/BF00999356
Kiyohiro Houkin, Ingrid L. Kwee, Tsutomu Nakada, Persistent high lactate level as a sensitive MR spectroscopy indicator of completed infarction. Journal of Neurosurgery. ,vol. 72, pp. 763- 766 ,(1990) , 10.3171/JNS.1990.72.5.0763
L. J. Gregory, M. J. O'Neill, J. A. Nunn, J. A. Gray, S. C. R. Williams, Diffusion-weighted magnetic resonance imaging detects early neuropathology following four vessel occlusion ischemia in the rat. Journal of Magnetic Resonance Imaging. ,vol. 14, pp. 207- 214 ,(2001) , 10.1002/JMRI.1175
Takaaki Kirino, Delayed neuronal death in the gerbil hippocampus following ischemia Brain Research. ,vol. 239, pp. 57- 69 ,(1982) , 10.1016/0006-8993(82)90833-2
K Houkin, K Kamada, H Kamiyama, Y Iwasaki, H Abe, T Kashiwaba, Longitudinal changes in proton magnetic resonance spectroscopy in cerebral infarction. Stroke. ,vol. 24, pp. 1316- 1321 ,(1993) , 10.1161/01.STR.24.9.1316
K. Minematsu, L. Li, M. Fisher, C. H. Sotak, M. A. Davis, M. S. Fiandaca, Diffusion‐weighted magnetic resonance imaging Rapid and quantitative detection of focal brain ischemia Neurology. ,vol. 42, pp. 235- 235 ,(1992) , 10.1212/WNL.42.1.235
Mauricio Castillo, Andres Arbelaez, Suresh K. Mukherji, Diffusion-weighted MR imaging of global cerebral anoxia. American Journal of Neuroradiology. ,vol. 20, pp. 999- 1007 ,(1999)