'Malignant' hypertension from hyperaldosteronism: a case report.

摘要: Adrenocortical carcinomas (ACC) are rare with an incidence of 0.7-2 per million population year and account for only 0.05%-2% all malignant tumors. While majority the functional ACC present as Cushing syndrome, recurrent hyperaldosteronism from metastatic is exceedingly rare. We describe a 67-year old female presented hypertensive urgency & hypokalemia result 8-cm right ACC. She underwent radical nephrectomy adrenalectomy that normalized her blood pressure. However, few years later she again resistant hypertension hyperaldosteronism, raising suspicion recurrence A contrast-enhanced CT scan showed normal left adrenal gland but revealed pulmonary metastases based on lung biopsy. Chemotherapy was complicated side effects leading to refusal further chemotherapy, henceforth requiring high dose spironolactone pressure control. Despite curative surgery, should be considered in patients presenting secondary due its rate. Besides standard cancer surveillance after meticulous monitoring simple yet crucial way detect early.